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. Author manuscript; available in PMC: 2025 Mar 1.
Published in final edited form as: Oral Surg Oral Med Oral Pathol Oral Radiol. 2023 Nov 26;137(3):264–273. doi: 10.1016/j.oooo.2023.11.012

Table 2.

Change in opening distance in millimeters from baseline to each visit and difference in change based on treatment characteristics. Estimate (95% CI); p-values are presented.

Change in
mouth
opening
distance		 Total RT dose
to primary site
 Treatment
per 100 cGy
greater dose		 RT only vs.
RT+CT		 RT only vs.
Sur+RT		 RT only vs.
Sur+RT+CT		 RT+CT vs.
Sur+RT		 RT+CT vs.
Sur+RT+CT		 Sur+RT vs.
Sur+RT+CT
p-value ≤0.0001 ≤0.0001 0.0073
V06 vs. BL −2.83
(−3.45, −2.2);
≤0.0001		 −0.19
(−0.31, −0.08);
0.0006		 1.62
(−0.94, 4.19);
0.2149		 −0.84
(−3.45, 1.77);
0.5297		 1.85
(−0.8, 4.51);
0.1715		 −2.46
(−3.98, −0.94);
0.0015		 0.23
(−1.36, 1.83);
0.7751		 2.69
(1.02, 4.36);
0.0016
V12 vs. BL −2.12
(−2.76, −1.47);
≤0.0001		 −0.17
(−0.27, −0.06);
0.0018		 1.66
(−0.97, 4.29);
0.2149		 −0.63
(−3.31, 2.06);
0.6471		 1.77
(−0.98, 4.52);
0.2072		 −2.29
(−3.85, −0.72);
0.0042		 0.11
(−1.57, 1.78);
0.9003		 2.40
(0.63, 4.16);
0.0077
V18 vs. BL −1.74
(−2.41, −1.06);
≤0.0001		 −0.23
(−0.33, −0.12);
≤0.0001		 3.32
(0.62, 6.02);
0.0159		 0.54
(−2.23, 3.30);
0.7030		 2.59
(−0.24, 5.42);
0.0728		 −2.79
(−4.42, −1.16);
0.0008		 −0.74
(−2.47, 1.00);
0.4067		 2.05
(0.22, 3.88);
0.0284
V24 vs. BL −1.83
(−2.49, −1.17);
≤0.0001		 −0.22
(−0.32, −0.11);
≤0.0001		 1.41
(−1.25, 4.08);
0.2992		 −1.71
(−4.42, 1.00);
0.2167		 0.73
(−2.07, 3.52);
0.6108		 −3.12
(−4.71, −1.53);
≤0.0001		 −0.69
(−2.41, 1.04);
0.4361		 2.43
(0.64, 4.23);
0.0079

RT: radiation therapy; CT: chemotherapy; Sur: surgery.