Table 2.
Summation of key behavioral and biochemical changes. Summary of significant behavioral and biochemical changes per sex following administration of p53-scmTNFR2 in EAE mice at days 10, 13, and 16 post-immunization.
| Females | Males | |
|---|---|---|
| Mechanical Hypersensitivity | ↓ Hypersensitivity | ↓ Hypersensitivity |
| Motor Disease | ↓ Severity + Delayed Onset | Same as control |
| Myelin Associated Proteins | Robust expression in cortex | Remains reduced |
| Microglial Activity | Cortical attenuation | Cortical attenuation |