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. Author manuscript; available in PMC: 2024 Mar 8.
Published in final edited form as: Chem Rev. 2024 Feb 2;124(3):1288–1320. doi: 10.1021/acs.chemrev.3c00727

Figure 2.

Figure 2.

Methanotroph metabolic pathways. The pMMO trimer is colored by protomer, showing its C3 symmetrical organization. sMMO is colored by subunits that comprise the complex, along with the MMO regulatory protein B (MMOB) bound (indigo) on the front and back (dashed line) sides of sMMO. MDH, methanol dehydrogenase; ICMs, intracytoplasmic membranes; PFLAs, phospholipid fatty acids; RuMP, ribulose monophosphate; CBB, Calvin-Benson-Bassham; H4MPT, tetrahydromethanopterin pathway; H4F, tetrahydrofolate pathway; FDH, formate dehydrogenase; SHMT, serine hydroxymethyltransferase; Hps, hexulose 6-phosphate synthase; RuBisCo, ribulose 1,5-bisphosphate carboxylase.