Skip to main content
. 2024 Feb 23;14:1278237. doi: 10.3389/fonc.2024.1278237

Table 2.

Pooled clinical characteristics of patients who underwent frozen autograft reconstruction.

Clinical characteristics Number of patients or value P
Gender
male 27 (63%)
female 16 (37%)
Age (year) 22.6 ± 15.6
Histology
osteosarcoma 30 (70%)
Ewing sarcoma 7 (16%)
chondrosarcoma 3 (7%)
others 3 (7%)
Primary site
femur 20 (46%)
tibia 14 (32%)
humerus 5 (12%)
radius 2 (5%)
ilium 2 (5%)
Length of autograft (cm) 16.9 ± 5.8
Whether the autograft contained articular surface of the knee joint
yes 5 (12%)
no 38 (88%)
Fixation with plate 43 (100%)
Average follow-up time (months) 31 (range 10–61)
Survival
yes 27 (63%)
no 16 (37%)
ISOLS score (%) <0.001
patients with the autograft containing the knee joint surface 28.2% ± 4.9%
patients with the autograft not containing the knee joint surface 80.6% ± 15%
Bone healing time (months) 0.0149
C site 9.8 ± 6.3
F site 14.9 ± 6.3
The site of Bone non-union
C site 0 (0%)
F site 7 (100%)
Complications
bone non-union 7
joint deformity 5
infection 1
recurrence 1
MSTS score (%) <0.001
patients with the autograft containing the knee joint surface 27.2% ± 4.4%
patients with the autograft not containing the knee joint surface 87% ± 11.6%

Data are presented as percentages (number events/total). ISOLS, International Society of Limb Salvage; C site, osteotomy site closer to the epiphysis; F site, osteotomy site far from the epiphysis; MSTS, Musculoskeletal Tumor Society.