TABLE 2.

Anti-mycobacterial activity of compound 1 against clinical isolates of M. avium

Clinical isolate	Resistance to	MIC (μg/mL)
		1	CAM	RFP	EB
M. avium 1	None	4.0	1.0	4.0	4.0
M. avium 2	CAM and EB	8.0	>64	2.0	>64
M. avium 3	CAM and EB	16	64	4.0	>64
M. avium 4	None	8.0	2.0	2.0	8.0
M. avium 5	CAM	4.0	>64	4.0	4.0
M. avium 6	CAM	8.0	>64	2.0	16
M. avium 7	CAM	16	>64	4.0	32
M. avium 8	None	8.0	2.0	8.0	8.0
M. avium 9	CAM	4.0	>64	16	16
M. avium 10	CAM and EB	16	>64	16	64
M. avium 11	CAM	2.0	64	2.0	16
M. avium 12	CAM and EB	8.0	>64	16	>64
M. avium 13	CAM and EB	32	>64	16	64
M. avium 14	CAM	2.0	>64	4.0	16
M. avium 15	CAM	4.0	>64	1.0	16
M. avium 16	None	8.0	2.0	4.0	16
M. avium 17	CAM and EB	8.0	>64	8.0	32
M. avium 18	CAM, RFP, and EB	8.0	>64	32	>64
M. avium 19	CAM	16	>64	16	16
M. avium 20	CAM, RFP, and EB	32	>64	>64	>64
M. avium 21	None	1.0	0.25	0.063	4.0
M. avium 22	None	4.0	1.0	1.0	4.0
M. avium 23	None	1.0	0.5	0.016	2.0
M. avium 24	CAM	1.0	32	0.031	4.0
M. avium 25	CAM and EB	1.0	>64	0.5	32
M. avium 26	None	4.0	1.0	1.0	16
M. avium 27	None	2.0	0.25	1.0	4.0
M. avium 28	None	2.0	0.5	0.031	8.0
M. avium 29	None	1.0	0.25	0.063	2.0
M. avium 30	CAM and RFP	1.0	>64	>64	4.0
M. avium 31	None	2.0	0.5	0.063	8.0
M. avium 32	None	2.0	0.5	0.063	4.0
M. avium 33	CAM	2.0	64	0.0078	4.0
M. avium 34	None	2.0	8.0	0.063	16
M. avium 35	None	4.0	1.0	0.031	16
M. avium 36	CAM and EB	1.0	64	0.063	32
M. avium 37	CAM	2.0	64	0.063	8.0
M. avium 38	CAM	1.0	32	0.0039	8.0
M. avium 39	None	1.0	8.0	0.13	8.0
M. avium 40	None	1.0	0.13	0.13	16
M. avium ATCC700898	Wild strain	3.12	0.39	0.04	6.25