Table 2.
Clinical characteristics of the study population
| Indicators | Value |
|---|---|
| Age (years) | 47.27±13.61 |
| Sex (male/female) | 45/6 |
| BMI (kg/m2) | 22.78±2.61 |
| AEtiology of chronic liver disease, n, (%) | |
| HBV | 45 (88.2) |
| HCV | 0 |
| Alcoholic hepatitis | 4 (7.8) |
| Drug induced liver injury | 0 |
| Autoimmune hepatitis | 0 |
| Wilson’s disease | 4 (7.8) |
| Other causes | 0 |
| Prognostic score before liver transplantation | |
| MELD score | 34.90±5.61 (21–41) |
| MELD ≤ 9 | 0 |
| MELD 10–19 | 0 |
| MELD 20–29 | 9 (17.65) |
| MELD 30–39 | 25 (49.02) |
| MELD ≥40 | 17 (33.33) |
| Average ACLF grade | 2.12±0.55 (1–3) |
| ACLF grade I | 5 (9.8) |
| ACLF grade II | 35 (68.6) |
| ACLF grade III | 11 (21.6) |
| Average AARC score | 9.43±1.68 (6–13) |
| Preoperative laboratory data | |
| Platelets (G/l) | 84.33±44.18 |
| PT (%) | 38.24±16.11 |
| INR | 2.36±1.04 |
| Lactate (mmol/l) | 2.87±2.51 |
| GOT (AST) (U/l) | 202.03±174.89 |
| GPT (ALT) (U/l) | 149.99 ±162.15 |
| GGT (U/l) | 61.56±46.78 |
| Serum albumin (g/l) | 33.13 ±4.18 |
| Serum total bilirubin (micromol/l) | 362.33 ±163.22 |
| Serum creatinine (micromol/l) | 90.18±±63.03 |
| Morbidity before liver transplantation | |
| Hepatic encephalopathy, n (%) | 19 (37.25) |
| Grade I, n (%) | 3 (5.88) |
| Grade II, n (%) | 5 (9.80) |
| Grade III, n (%) | 4 (7.84) |
| Grade IV, n (%) | 7 (13.73) |
| Hepatorenal syndrome, n (%) | 7 (13.73) |
| Infection, n (%) | 9 (17.65) |
| The number of patients that require PEX, n (%) | 36 (70.6) |
| Average number of times (n=36) | 3.28±2.75 |
| CMV infected, n (%) | 7 (13.73) |
AARC, The APASL ACLF Research Consortium; ACLF, acute-on-chronic liver failure; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CMV, cytomegalovirus; GGT, gamma-glutamyl transferase; GOT, glutamic oxaloacetic transaminase; GPT, glutamate pyruvate transaminase; HBV, hepatitis B virus; HCV, hepatitis C virus; INR, international normalized ratio; MELD, model for end-stage liver disease; PEX, plasma exchange; PT, prothrombin time.