TABLE 1.

CD2366 inhibits RARβ2 mRNA induction by RA

Treatment (concn)	ODa
	RARα	RARβ	RARγ
Control	8.39	0	0.51
CD2366 (1 μM)	8.50	0	0.57
RA (10 nM)	8.60	0.24	0.53
RA (100 nM)	9.10	0.33	0.56
CD2366 (1 μM) + RA (10 nM)	8.50	0	0.54
CD2366 (1 μM) + RA (100 nM)	9.00	0.15	0.51

^aOptical density (OD) values were obtained by densitometric scanning of the gel. RNA transcripts of the β-actin gene were used to normalize RT-PCR assays. The experiment was conducted twice with very similar results.