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. 2024 Mar 8;19(3):e0277847. doi: 10.1371/journal.pone.0277847

Table 1. Associations between demographic and clinical variables and time to full enteral feeds; univariate analysis.

Variable Median tFEF (IQR) in Days p value Effect size (r)
Sex
    • Female 7.5 (4.3, 12) 0.976 -0.002
    • Male 8 (5, 12)
By GA
    • 32-<37 weeks 6 (4, 9)
    • 28 <32weeks 8 (6, 12) 0.003* 0.16
    • <28 weeks 8 (4,12)
By Birthweight
    • 1–1.5kg 8 (5, 12) 0.482 0.05
    • <1kg 8 (5, 14)
Weight Centiles
    • AGA 8 (5, 12) 0.933 0.006
    • SGA 8 (5, 12)
Length Centiles
    • Not Stunted 8 (3, 13) 0.107 -0.114
    • Stunted 7 (4, 11)
Weight/Length Ratio Centiles
    • Not Wasted 8 (6, 13) 0.200 -0.090
    • Wasted 7 (4,11)
First Feed: colostrum/breastmilk
    • Yes 7 (4, 12) 0.148 0.091
    • No 9 (6, 12)
First Feed: Preterm Formula
    • No 7 (4, 12) 0.312 0.064
    • Yes 9 (5, 12)
First Feed: Standard Formula
    • No 8 (4, 12) 0.374 0.056
    • Yes 5.5 (5.3, 8)
Asphyxia
    • No 8 (5,12) 0.610 -0.032
    • Yes 7 (4, 10)
Respiratory Distress
    • No 8 (5, 13) 0.001 * 0.201
    • Yes 7 (4, 10)
Sepsis
    • No 8 (4, 12) 0.822 -0.014
    • Yes 7 (5, 10)
Abdominal Conditions
    • No 7 (4, 11) 0.004 * 0.182
    • Yes 16 (7.5, 24.5)

tFEF = time to full enteral feeds; IQR interquartile range; GA = gestational age; AGA = appropriate for gestational age; SGA = small for gestational age

* significant p value.