Fig. 4. Opportunities and needs for biomaterial models of dormancy.
Top: Illustrative examples of several examples of existing biomaterials technologies that exist for studies in tissue engineering, cancer models, etc. but have not yet been applied to studies in cancer dormancy. Bottom: Illustrations of technologies that are of critical need to effectively study dormancy in vitro but that do not yet exist. For example, current biomaterials do not allow to follow, in real-time, dynamic transitions between cell or tumor dormancy and relapse states, or observe the ability of immune cells to edit tumors and keep them in a dormant state. Figure created in BioRender.
