Figure 2.

Visual schematic of study procedures and correlative research (with time points). Patients will undergo intraoperative delivery of AMSCs encapsulated in fibrin glue to the resection cavity immediately after tumor excision. An ipsilateral CSF reservoir will also be placed at the time of surgery and will be used to collect CSF samples throughout the study. Tissue will undergo immunohistochemistry to evaluate immune infiltration and the long-term presence of AMSCs within the tissue. An inflammatory cytokine profile and next generation sequencing will be performed in all CSF and blood samples.