. Author manuscript; available in PMC: 2024 Apr 1.

Published in final edited form as: Curr Protoc. 2023 Apr;3(4):e734. doi: 10.1002/cpz1.734

Table 2: Comparison of SNP-heritability ( ${\hat{h}}_{S N P}^{2}$ ) of Height and BMI utilizing widely used approaches:

N represents the number of samples used for the analyses; SC, MS, LDMS-R, LDMS-I represent single component, MAF stratified, Regional LD scores and MAF stratified, SNP LD score and MAF stratified, respectively. P-values were calculated using one sided z test.

Approach	Height (N = 3997)			BMI (N = 3985)

	${\hat{h}}_{S N P}^{2}$	S.E.	P-Value	${\hat{h}}_{S N P}^{2}$	S.E.	P-Value
GREML-SC	0.5835	0.0658	< 1.11E-16	0.2494	0.0694	1.65E-04

GREML-MS	0.5867	0.0671	< 1.11E-16	0.2713	0.0719	8.06E-05

GREML-LDMS-R	0.6171	0.0719	< 1.11E-16	0.2811	0.0774	1.40E-04

GREML-LDMS-I	0.6152	0.0743	< 1.11E-16	0.2528	0.0811	9.13E-04

LDAK-Thin	0.5688	0.0647	< 1.11E-16	0.2571	0.0683	8.37E-05

LDAK-Thin-MS	0.5976	0.0684	< 1.11E-16	0.2527	0.0729	2.64E-04

LDAK	0.6183	0.0710	< 1.11E-16	0.2625	0.0761	2.81E-04

LDAK-MS	0.6173	0.0725	< 1.11E-16	0.2599	0.0781	4.38E-04

Threshold GRMs	0.5836	0.0656	< 1.11E-16	0.2509	0.0695	1.53E-04

LD Score Regression	0.4552	0.0193	< 1.11E-16	0.1908	0.0053	< 1.11E-16

SumHer	0.6785	0.0077	< 1.11E-16	0.2844	0.0078	< 1.11E-16

Table 2: Comparison of SNP-heritability (h^SNP2) of Height and BMI utilizing widely used approaches:

Table 2: Comparison of SNP-heritability ( ${\hat{h}}_{S N P}^{2}$ ) of Height and BMI utilizing widely used approaches: