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. 2024 Mar 8;9:54. doi: 10.1038/s41541-024-00836-w

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Viremia was quantified by qRT-PCR and data expressed as mean viral copies/mL ( = SD; = FD). Dashed line represents limit of detection (LOD): 3.45 Log10 copies/mL. b YF-specific IgM ( = SD; = FD) and (c) IgG ( = SD; = FD) were measured in-house ELISA and data expressed as mean OD for IgM and as mean IU/mL for IgG. d YF-specific neutralizing antibodies test was quantified by μPRN-HRP assay and data reported as GeoMean of reciprocal of serum dilution ( = SD; = FD). The results are reported as scattering distribution of individual data at distinct timepoints (D0 / D1-3 = ; D4-5 = ; D6-7 = ; D7-15 / D8/15 = ; D30-45 = ). Dotted lines represent the gray zone. Data above gray background was considered positive. Significant intragroup differences are identified by Kruskal–Wallis test are represented by *p < 0.05; ****p < 0.0001. Intergroups differences in μPRN-HRP GeoMean, identified by Student t-test and represented by #.

Inline graphic — a Viremia was quantified by qRT-PCR and data expressed as mean viral copies/mL ( = SD; = FD). Dashed line represents limit of detection (LOD): 3.45 Log10 copies/mL. b YF-specific IgM ( = SD; = FD) and (c) IgG ( = SD; = FD) were measured in-house ELISA and data expressed as mean OD for IgM and as mean IU/mL for IgG. d YF-specific neutralizing antibodies test was quantified by μPRN-HRP assay and data reported as GeoMean of reciprocal of serum dilution ( = SD; = FD). The results are reported as scattering distribution of individual data at distinct timepoints (D0 / D1-3 = ; D4-5 = ; D6-7 = ; D7-15 / D8/15 = ; D30-45 = ). Dotted lines represent the gray zone. Data above gray background was considered positive. Significant intragroup differences are identified by Kruskal–Wallis test are represented by *p < 0.05; ****p < 0.0001. Intergroups differences in μPRN-HRP GeoMean, identified by Student t-test and represented by #.