Table 4.
Potential risk factor for relapse after IN discontinuation.
| Relapse within a year (N = 50) | More than 1-year remission (N = 22) | Univariate analyses (P value) | Multivariate analyses (P value) | |
|---|---|---|---|---|
| Age at diagnosis, years; mean (± SD) | 29.2 (± 15.1) | 25.9 (± 11.2) | 0.259 | |
| Disease duration, years; mean (± SD) | 8.4 (± 7.8) | 8.1 (± 6.8) | 0.855 | |
| Extent of disease (extensive/left-side proctitis) | 27/23 (54%/46%) | 15/7 (68.1%/31.8%) | 0.261 | 0.318 |
| Duratioin of IN use, week; mean (± SD) | 29 (± 41) | 21.4 (± 11.2) | 0.497 | 0.983 |
| Amount of IN used, g; mean (± SD) | 223 (± 230) | 188 (± 105) | 0.836 | |
| Previous corticosteroid use | 37 (74%) | 13 (59.0%) | 0.373 | 0.108 |
| Biologic naive | 30 (60%) | 13 (59.0%) | 0.771 | 0.236 |
| Albumin (mg/dL) at IN discontinuation | 4.49 (± 0.42)/13.4% | 4.54 (± 0.31)/10.5% | 0.366 | |
| Hemoglobin (g/dL) at IN discontinuation | ||||
| Male | 13.4 (± 1.55) | 14.4 (± 1.63) | 0.107 | |
| Female | 12.4 (± 1.62) | 12.8 (± 0.74) | 0.152 | |
Data are presented as mean (± SD) and number (percentage).
IN indigo naturalis, SD standard deviation.