Table 2.
Multivariable logistic regression analysis for risk of venous thromboembolism in geriatric trauma patients with isolated severe traumatic brain injury
| Risk factor | OR | CI | p-value |
|---|---|---|---|
| LMWH vs. UH | 0.83 | 0.63–1.08 | 0.171 |
| Hypotensive on admsision | 1.93 | 1.00–3.76 | 0.053 |
| Blood Transfusion | 1.57 | 0.96–2.60 | 0.075 |
| Any surgical intervention | 2.33 | 1.80–3.01 | < 0.001 |
| Male Sex | 1.55 | 1.20–2.01 | < 0.001 |
| Craniotomy/craniectomy within first 24 h | 1.09 | 0.54–2.22 | 0.809 |
| Age > 75 years | 1.16 | 0.90–1.47 | 0.248 |
| Time to Prohylaxis (days) | |||
| ≤ 2 | REFERENCE | ||
| 3 | 1.22 | 0.78–1.91 | 0.378 |
| ≥ 4 | 2.71 | 1.85–3.97 | < 0.001 |
| Injury Severity Score | |||
| < 9 | REFERENCE | ||
| 9–15 | 0.853 | 0.49–1.47 | 0.568 |
| 16–24 | 1.30 | 0.68–2.51 | 0.43 |
| ≥ 25 | 2.85 | 0.71–11.40 | 0.138 |
| Total GCS | |||
| 14–15 | REFERENCE | ||
| 9–13 | 1.48 | 1.08–2.01 | 0.13 |
| 3–8 | 1.84 | 1.32–2.55 | < 0.001 |
| AIS-Head (grade) | |||
| 3 | REFERENCE | ||
| 4 | 0.82 | 0.50–1.34 | 0.430 |
| 5 | 0.52 | 0.14–1.91 | 0.321 |
| CHF | 1.01 | 0.66–1.55 | 0.968 |
| COPD | 1.05 | 0.71–1.58 | 0.782 |
| Diabetes | 1.11 | 0.85–1.44 | 0.454 |
| Hypertension | 1.38 | 1.05–1.81 | 0.020 |
| CKD | 0.956 | 0.48–1.90 | 0.899 |
LMWH low molecular weight heparin, UH unfractionated heparin, GCS Glasgow Coma Scale, AIS Abbreviated Injury Scale, CHF Congestive Heart Failure, COPD Chronic Obstructive Pulmonary Disease, CKD Chronic Kidney Disease