Table 3.
Multivariable logistic regression analysis for risk of mortality in geriatric trauma patients with isolated severe traumatic brain injury
| Risk Factor | OR | CI | p-value |
|---|---|---|---|
| LMWH vs. UH | 0.77 | 0.66–0.91 | 0.001 |
| Hypotensive on admsision | 1.87 | 1.21–2.9 | 0.005 |
| Blood Transfusion | 1.67 | 1.23–2.29 | 0.001 |
| Any surgical intervention | 1.60 | 1.36–1.88 | < 0.001 |
| Male Sex | 1.40 | 1.20–1.63 | < 0.001 |
| Craniotomy/craniectomy within first 24 h | 1.98 | 1.35–2.884 | < 0.001 |
| Age > 75 years | 1.86 | 1.60–2.18 | < 0.001 |
| Time to Prohylaxis (days) | |||
| ≤ 2 | REFERENCE | ||
| 3 | 1.03 | .882–1.29 | 0.793 |
| ≥ 4 | 1.24 | 1.20–1.77 | 0.036 |
| Injury Severity Score | |||
| < 9 | REFERENCE | ||
| 9–15 | 0.86 | 0.60–1.28 | 0.494 |
| 16–24 | 1.09 | 0.67–1.77 | 0.729 |
| ≥ 25 | 1.94 | 0.772–5.25 | 0.188 |
| Total GCS | |||
| 14–15 | REFERENCE | ||
| 9–13 | 2.51 | 2.13–3.08 | < 0.001 |
| 3–8 | 4.67 | 3.86–5.67 | < 0.001 |
| AIS-Head (grade) | |||
| 3 | REFERENCE | ||
| 4 | 1.41 | 0.98–2.04 | 0.066 |
| 5 | 1.75 | 0.69–4.48 | 0.237 |
| CHF | 1.52 | 1.20–1.91 | < 0.001 |
| COPD | 1.21 | 0.95–1.53 | 0.124 |
| Diabetes | 1.18 | 1.00–1.38 | 0.048 |
| Hypertension | 0.83 | 0.70–0.97 | 0.018 |
| CKD | 1.81 | 1.27–2.57 | < 0.001 |
LMWH low molecular weight heparin, UH unfractionated heparin, GCS Glasgow Coma Scale, AIS Abbreviated Injury Scale, CHF Congestive Heart Failure, COPD Chronic Obstructive Pulmonary Disease, CKD Chronic Kidney Disease