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. 2024 Mar 1;71(3):378–389. doi: 10.1007/s12630-024-02692-7

Table 2.

Descriptive statistics of laboratory data of patients with viral sepsis, patients with nonviral sepsis (T1 and T2), and healthy volunteers

Variable Time VS n NVS n HV n P valuea
VS vs NVS VS vs HV NVS vs HV
AChE (U·L−1), median [IQR] T1 5,105 [4,010–6,250] 108 4,424 [3,630–5,055] 117 6,693 [5,401–8,020] 81  < 0.001  < 0.001  < 0.001
T2 4,766 [3,732–6,235] 99 4,189 [3,397–4,783] 108 - -  < 0.001  < 0.001b  < 0.001b
BChE (U·L−1), median [IQR] T1 1,943 [1,393–2,468] 108 1,095 [834–1,526] 117 2,645 [2,198–3,478] 81  < 0.001  < 0.001  < 0.001
T2 1,932 [1,427–2,595] 99 1,114 [864–1,549] 108 - -  < 0.001  < 0.001b  < 0.001b
Hb (mmol·L−1), median [IQR] T1 7.4 [6.4–8.0] 108 5.3 [4.9–5.8] 116 9.1 [8.6–9.6] 81  < 0.001  < 0.001  < 0.001
T2 6.9 [5.8–7.7] 98 5.3 [4.9–5.9] 103 - -  < 0.001  < 0.001b  < 0.001b
Albumin (g·L−1), median [IQR] T1 30.0 [25.0–32.0] 107 21.0 [17.5–25.0] 117 43.0 [40.0–46.0] 81  < 0.001  < 0.001  < 0.001
T2 29.0 [25.0–33.0] 94 21.0 [17.0–26.3] 106 - -  < 0.001  < 0.001b  < 0.001b
ChE (µmol·L−1), median [IQR] T1 88.0 [71.0–105.0] 107 39.0 [26.0–57.0] 117 146.0 [129.5–165.0] 81  < 0.001  < 0.001  < 0.001
T2 87.0 [64.0–109.3] 94 42.0 [30.0–58.0] 103 - -  < 0.001  < 0.001b  < 0.001b
CRP (mg·L−1), median [IQR] T1 63.4 [32.5–124.4] 108 200.8 [129.9–285.7] 116 2.0 [0.6–2.2] 81  < 0.001  < 0.001  < 0.001
T2 34.6 [14.7–80.6] 98 102.2 [63.8–157.3] 101 - -  < 0.001  < 0.001b  < 0.001b
PCT (ng·L−1), median [IQR] T1 0.18 [0.09–0.48] 108 3.80 [1.07–13.92] 116 - -  < 0.001 - -
T2 0.14 [0.07–0.32] 98 0.89 [0.33–2.74] 106 - -  < 0.001 - -
Ferritin (µg·mL−1), median [IQR] T1 1,287.2 [833.6–2,151.6] 104 - - - - - - -
T2 1,310.3 [696.3–1,816.2] 94 - - - - - - -
IL-6 (pg·mL−1), median [IQR] T1 31.4 [10.3–82.4] 105 - - - - - - -
T2 16.5 [6.4–160.0] 95 - - - - - - -

aMann–Whitney U test (P < 0.05 are marked in bold)

bData of patients with viral or nonviral sepsis from T2 was compared with healthy controls (T1)

AChE = acetylcholinesterase; BChE = butyrylcholinesterase; CRP = C-reactive protein; ChE = cholinesterase; Hb = hemoglobin; HV = healthy volunteers; IL-6 = interleukin-6; IQR = interquartile range; NVS = patients with nonviral sepsis; PCT = procalcitonin; T1 = 3 ± 1 days after onset of sepsis; T2 = 7 ± 1 days after onset of sepsis; VS = patients with viral sepsis