Table 3.
Associations between AChE and BChE activities with inflammatory markers and laboratory data of patients with viral sepsis
| Variable | AChE | BChE | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Time | ρa | 95% CI | P value | n | ρa | 95% CI | P value | n | |||
| Hb (mmol·L−1) | T1 | 0.51 | 0.35 | 0.63 | < 0.001 | 108 | 0.13 | −0.06 | 0.31 | 0.19 | 108 |
| T2 | 0.38 | 0.19 | 0.54 | < 0.001 | 97 | 0.20 | 0.00 | 0.38 | 0.049 | 97 | |
| Albumin (g·L−1) | T1 | 0.23 | 0.04 | 0.40 | 0.02 | 107 | 0.36 | 0.19 | 0.52 | < 0.001 | 107 |
| T2 | 0.29 | 0.09 | 0.47 | 0.004 | 93 | 0.35 | 0.16 | 0.52 | < 0.001 | 93 | |
| ChE (µmol·L−1) | T1 | 0.19 | 0.00 | 0.37 | 0.048 | 107 | 0.55 | 0.40 | 0.67 | < 0.001 | 107 |
| T2 | 0.23 | 0.03 | 0.41 | 0.03 | 93 | 0.51 | 0.34 | 0.65 | < 0.001 | 93 | |
| PCT (ng·L−1) | T1 | −0.17 | −0.35 | 0.02 | 0.08 | 108 | −0.29 | −0.45 | −0.11 | 0.002 | 108 |
| T2 | −0.17 | −0.36 | 0.03 | 0.09 | 97 | −0.27 | −0.44 | −0.07 | 0.008 | 97 | |
| CRP (mg·L−1) | T1 | −0.19 | −0.36 | 0.00 | 0.05 | 108 | −0.25 | −0.42 | −0.06 | 0.01 | 108 |
| T2 | −0.24 | −0.42 | −0.05 | 0.02 | 97 | −0.34 | −0.51 | −0.15 | < 0.001 | 97 | |
| Ferritin (µg·mL−1) | T1 | 0.16 | −0.03 | 0.35 | 0.10 | 104 | 0.05 | −0.15 | 0.24 | 0.62 | 104 |
| T2 | 0.05 | −0.15 | 0.25 | 0.63 | 93 | −0.01 | −0.21 | 0.20 | 0.95 | 93 | |
| IL–6 (pg·mL−1) | T1 | −0.03 | −0.22 | 0.16 | 0.75 | 105 | −0.06 | −0.25 | 0.14 | 0.57 | 105 |
| T2 | −0.21 | −0.40 | −0.01 | 0.04 | 94 | −0.26 | −0.44 | −0.06 | 0.01 | 94 | |
aSpearman’s rank correlation coefficient with 95% CI and P value (P < 0.05 are printed in bold)
AChE = acetylcholinesterase; BChE = butyrylcholinesterase; CI = confidence interval; CRP = C-reactive protein; ChE = cholinesterase; Hb = hemoglobin; IL-6 = interleukin-6; PCT = procalcitonin; SOFA = sequential organ failure assessment score; T1 = 3 ± 1 days after onset of sepsis; T2 = 7 ± 1 days after onset of sepsis