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. Author manuscript; available in PMC: 2024 Apr 15.
Published in final edited form as: Biol Psychiatry. 2023 Sep 9;95(8):745–761. doi: 10.1016/j.biopsych.2023.08.023

Figure 1.

Figure 1.

S-PrediXcan analysis identifies 89 unique genes associated with chronic pain. (A) S-PrediXcan analyses identified 89 unique significant gene associations across 14 tissues. Red line indicates most conservative per-tissue significance threshold. (B) Number of significant multisite chronic pain–genetically regulated gene expression genes per brain region. Created using cerebroViz (157). AMY, amygdala; CAU, caudate; CB, cerebellum; CNG, anterior cingulate cortex; FL, frontal lobe; HIP, hippocampus; HTH, hypothalamus; PUT, putamen; SN, substantia nigra.