Fig. 5.

MICOM model-based flux balance analysis of keystone taxa at time point 2. The 40 most predictive production fluxes (metabolites) are shown for the verum subgroup that had complaints after aronia juice consumption (Vc) on the left and the verum subgroup that tolerated the juice well (Vt) on the right using L1 penalized logistic regression. The analysis was based on 16S rRNA gene amplicons and the identified keystone taxa of the samples collected at the time point 2 which was directly after the intervention. In Vc, ammonium and carbon dioxide are highlighted in violet, and O-glycans are highlighted in red. In Vt, bile acids and bile acid anions are highlighted in orange