Fig. 1.

TYROBP network is upregulated in HD brains. STRING-generated interaction network of the common differentially expressed genes (DEGs) detected by RNA-seq in HD brains. STRING v11.5 was used to derive the network of 221 DEGs applying following prediction methods: text mining, experiments, databases, co-expression, neighborhood, gene fusion, co-occurrence. The nodes that did not interact with other nodes were deleted. The blue nodes illustrate genes/proteins assigned to “immune system process” Gene Ontology pathway. Line thickness indicates the strength of data support. Interaction score > 0.7