Table 3.
pfmdr1 mutations among samples collected in the eight regions from 2016 to 2021
| Year | Region | #Sequenced | pfmdr1* R1, n (%) | N86, n (%) | Y184, n (%) | 184F n (%) | pfmdr1* R2, n (%) | D1246 n (%) | 1246Y n (%) |
|---|---|---|---|---|---|---|---|---|---|
| 2016 | Kigoma | 118 | 118 (100.0) | 118 (100.0) | 78 (66.1) | 40 (33.9) | 118 (100.0) | 118 (100.0) | 0 (0.0) |
| Morogoro | 104 | 104 (100.0) | 104 (100.0) | 67 (64.4) | 37 (35.6) | 104 (100.0) | 103 (99.0) | 1 (1.0) | |
| Pwani | 92 | 92 (100.0) | 92 (100.0) | 51 (55.4) | 41 (44.6) | 92 (100.0) | 92 (100.0) | 0 (0.0) | |
| Tanga | 109 | 109 (100.0) | 109 (100.0) | 62 (56.9) | 47 (43.1) | 109 (100.0) | 108 (99.1) | 1 (0.9) | |
| 2018 | Kigoma | 111 | 110 (99.1) | 110 (99.1) | 76 (69.1) | 34 (30.9) | 104 (93.7) | 104 (100.0) | 0 (0.0) |
| Morogoro | 99 | 94 (94.9) | 94 (94.9) | 69 (73.4) | 25 (26.6) | 86 (86.9) | 86 (100.0) | 0 (0.0) | |
| Pwani | 97 | 86 (88.7) | 86 (88.7) | 53 (61.6) | 33 (38.4) | 87 (89.7) | 87 (100.0) | 0 (0.0) | |
| Tanga | 119 | 111 (93.3) | 111 (93.3) | 56 (50.5) | 55 (49.5) | 102 (85.7) | 102 (100.0) | 0 (0.0) | |
| 2019 | Mbeya | 95 | 88 (92.6) | 88 (92.6) | 48 (54.5) | 40 (45.5) | 84 (88.4) | 84 (100.0) | 0 (0.0) |
| Mtwara | 93 | 89 (95.7) | 89 (95.7) | 56 (62.9) | 33 (37.1) | 89 (95.7) | 89 (100.0) | 0 (0.0) | |
| Tabora | 111 | 98 (88.3) | 98 (88.3) | 68 (69.4) | 30 (30.6) | 97 (87.4) | 97 (100.0) | 0 (0.0) | |
| Mwanza | 104 | 96 (92.3) | 96 (92.3) | 67 (69.8) | 29 (30.2) | 102 (98.1) | 102 (100.0) | 0 (0.0) | |
| 2020 | Pwani | 97 | 90 (92.8) | 90 (92.8) | 38 (42.2) | 53 (58.9) | 79 (81.4) | 79 (100 .0) | 0 (0.0) |
| Kigoma | 103 | 92 (89.3) | 92 (89.3) | 61 (66.3) | 31 (33.7) | 65 (63.1) | 64 (98.5) | 1 (1.5) | |
| Morogoro | 96 | 91 (94.8) | 91 (94.8) | 54 (59.3) | 39 (42.9) | 85 (88.5) | 84 (98.8) | 1 (1.2) | |
| Tanga | 116 | 105 (90.5) | 105 (90.5) | 51 (48.6) | 55 (52.4) | 101 (87.1) | 101 (100.0) | 0 (0.0) | |
| 2021 | Mbeya | 48 | 35 (72.9) | 35 (72.9) | 17 (48.6) | 18 (51.4) | 34 (70.8) | 34 (100.0) | 0 (0.0) |
| Mtwara | 87 | 86 (98.9) | 86 (98.9) | 34 (39.5) | 52 (60.5) | 65 (74.7) | 65 (100.0) | 0 (0.0) | |
| Mwanza | 106 | 105 (99.1) | 105 (99.1) | 44 (41.9) | 61 (58.1) | 94 (88.7) | 94 (100.0) | 0 (0.0) | |
| Tabora | 110 | 109 (99.1) | 109 (99.1) | 59 (54.1) | 50 (45.9) | 77 (70.0) | 77 (100.0) | 0 (0.0) | |
| Total | 2015 | 1908 (94.7) | 1906 (99.9) | 1109 (58.1) | 803 (42.0) | 1774 (88.0) | 1770 (99.0) | 4 (0.2) |
*number of samples which passed the sequencing quality score criteria, n = number of samples. % = percentage of samples analyzed or with a particular genotype