Table 1.
Baseline Characteristics of Renal Transplant Recipients by Early Post-transplant Positive Culture Status, 2005–2021 (n = 3432)
| Variables | Study Population, n = 3432 | Negative Controls, n = 3138 | Early Post-transplant Positive Culture, n = 294 | |
|---|---|---|---|---|
| CSO n = 263 | MDRO, n = 31 | |||
| Age, median [IQR], y | 51 [40–60] | 50 [40–60] | 53 [43–63] | 55 [46–63] |
| Sex, No. (%) | ||||
| Female | 1453 (42) | 1274 (41) | 162 (62) | 17 (55) |
| Race, No. (%) | ||||
| Black | 1749 (51) | 1607 (51) | 128 (49) | 14 (45) |
| White | 1395 (41) | 1271 (41) | 109 (41) | 15 (48) |
| Biracial | 13 (0.4) | 12 (0.4) | 1 (0.4) | 0 (0) |
| Other | 252 (8) | 226 (8) | 4 (11) | 22 (9) |
| Unknown | 134 (4) | 122 (4) | 11 (4) | 1 (3) |
| Primary ESRD etiology, No. (%) | ||||
| Diabetes mellitus | 1054 (31) | 945 (30) | 99 (38) | 10 (32) |
| Hypertension | 858 (25) | 796 (25) | 49 (19) | 13 (42) |
| Glomerular disease | 665 (21) | 611 (21) | 4 (11) | 50 (19) |
| Polycystic kidney disease | 308 (9.0) | 293 (9.3) | 13 (5) | 2 (7) |
| Other | 494 (14) | 443 (14) | 48 (18) | 3 (10) |
| Transplant type, No. (%) | ||||
| Kidney | 3201 (93) | 2934 (93) | 240 (91) | 27 (87) |
| Kidney-pancreas | 229 (6.7) | 202 (6) | 23 (9) | 4 (13) |
| Kidney-liver | 2 (<0.01) | 2 (<0.01) | 0 (0) | 0 (0) |
| Transplant year, No. (%) | ||||
| 2005–2009 | 674 (20) | 620 (20) | 50 (19) | 4 (13) |
| 2010–2015 | 1188 (35) | 1056 (34) | 118 (45) | 14 (45) |
| 2016–2020 | 1570 (46) | 1462 (47) | 95 (36) | 13 (42) |
| Donor type, No. (%) | ||||
| Deceased | 2332 (68) | 2107 (67) | 200 (76) | 25 (81) |
| Living | 1100 (32) | 1031 (33) | 63 (24) | 6 (19) |
| Years on dialysis, median [IQR] | 4.4 [2.2–7.3] | 4.4 [2.2–7.3] | 4.7 [2.4–7.4] | 7.0 [3.8–10.3] |
| Missing, No. (%) | 1021 (29) | 933 (30) | 80 (30) | 8 (26) |
| Immune induction protocol, No. (%) | ||||
| Basiliximab | 2466 (72) | 2256 (72) | 188 (71) | 22 (71) |
| Thymoglobulin | 605 (18) | 541 (17) | 56 (21) | 8 (26) |
| Other | 361 (11) | 341 (11) | 19 (7) | 1 (3) |
| CMV status, No. (%) | ||||
| D-/R- | 402 (12) | 376 (12) | 260 (9) | 3 (10) |
| D-/R+ or D+/R+ | 2454 (72) | 2228 (72) | 201 (77) | 25 (83) |
| D+/R- | 529 (16) | 491 (16) | 36 (14) | 2 (7) |
| Missing | 47 (1) | 43 (1) | 3 (1) | 1 (3) |
| Rejection within first year post-transplant | 441 (13) | 399 (13) | 38 (14) | 4 (13) |
| MDRO detected pretransplant | 67(2) | 58(2) | 7(3) | 2(7) |
| Transplant admission LOS, median [IQR], d | 4.0 [3.0–6.0] | 4.0 [3.0–6.0] | 5.0 [4.0–8.0] | 7.0 [4.0–15.0] |
| Missing, No. (%) | 1 | 1 | 0 | 0 |
Abbreviations: CSO, comparative antibiotic-susceptible organism; D, donor; ESRD, end-stage renal disease; IQR, interquartile range; LOS, length of stay; MDRO, multidrug-resistant organism; R, recipient.