Table 2.
Minimum inhibitory concentrations of various unrelated classes of antibiotics against M. smegmatis cells harbouring pMIND vector (control of M. smegmatis cells) and Rv3270 (pM3270) in the presence and absence of reserpine (32 µg ml−1)
|
Antibiotic |
MIC (mg l−1) |
|||
|---|---|---|---|---|
|
Reserpine (32 µg ml−1) |
||||
|
M. smegmatis MC2155 |
M. smegmatis MC2155/pM3270 |
M. smegmatis MC2155 |
M. smegmatis MC2155/pM3270 |
|
|
Norfloxacin |
2 |
8 |
0.5 |
0.5 |
|
Ofloxacin |
0.5 |
2 |
0.5 |
1 |
|
Sparfloxacin |
2 |
8 |
1 |
2 |
|
Ampicillin |
32 |
128 |
8 |
8 |
|
Oxacillin |
16 |
64 |
8 |
16 |
|
Amikacin |
4 |
8 |
2 |
2 |
|
Isoniazid |
32 |
256 |
8 |
8 |
|
Levofloxacin |
2 |
2 |
2 |
2 |
|
Levofloxacin+Zn2+ |
2 |
8 |
1 |
1 |
|
Apramycin |
8 |
8 |
8 |
8 |
|
Apramycin+Zn2+ |
8 |
16 |
8 |
16 |
|
Rifampicin |
1 |
1 |
1 |
1 |
|
Rifampicin+Zn2+ |
1 |
2 |
0.5 |
0.5 |