Fig. 1.

Biofilm variants are altered in their ability to replicate within J774A.1 macrophage-like cells. Gentamicin protection assays were performed using natural biofilm forming variants of (a) FRAN244 (Type A) and (b) FRAN255 (Type B). CFUs were determined at 4 h (black bars) and 24 h (grey bars) post infection. Error bars represent the standard error of the mean from three independent experiments. Significance was assessed using linear mixed effects model on log10 transformed data. *p <0.05, ****p<0.0001.