Table 6.
Phenotypic summary of isolates recovered from challenged mice at 21 days post-challenge
|
Strain |
Challenge dose (c.f.u.) |
# of mice w/ detectable LVS |
Avg c.f.u. Recovered* |
Colony morphology |
LPS status† |
Biofilm Formation |
|---|---|---|---|---|---|---|
|
LVS wild-type |
470 |
5/5 |
204 |
Normal |
nd |
nd |
|
Isolate #15 |
450 |
0/5 |
0 |
|||
|
45 000 |
10/10 |
174 |
Normal |
Blue form |
Negative |
|
|
ΔwbtJ |
490 |
1/5 |
20 |
Small |
Grey form |
Positive |
|
49 000 |
2/10 |
25 |
Small |
Grey form |
Positive |
|
*Based on plating homogenate from the complete spleen.
†As determined by western blot analysis using mAb specific to F. tularensis O-Ag.