Central Illustration: Age-Specific N-Terminal B-Type Natriuretic Peptide Concentrations Stratified by Age and Race and Ethnicity.

The age-specific 2.5^th, 25^th, 50^th, 75^th, and 97.5^th centiles of N-terminal pro-B-type natriuretic peptide (NT-proBNP) stratified by sex and race and ethnicity in individuals below 40 years of age have been depicted. The panel on the left depicts sex-stratified NT-proBNP concentrations. Males have been depicted as solid lines and females have been depicted as dashed lines. The percentage difference of NT-proBNP in females compared with males per 10-year age group has been depicted. The panel on the right depicts race and ethnicity stratified NT-proBNP concentrations. Non-Hispanic White, non-Hispanic Black, and Mexican American individuals have been depicted as dotted, dashed, and solid lines, respectively. The percentage difference of NT-proBNP in non-Hispanic Black and Mexican American individuals compared with non-Hispanic White individuals per 10-year age group has been depicted. In both panels, the 2.5^th, 25^th, 50^th, 75^th, and 97.5^th centiles of NT-proBNP have been depicted in red, yellow, purple, green, and blue, respectively.