Table 3.
Univariate and Multivariate Logistic Regression Analysis of Factors Affecting Drainage Tube Retention Time in Patients with Breast Cancer
| n | Level | Univariate | Multivariate | ||||||
|---|---|---|---|---|---|---|---|---|---|
| OR | 95% CI low | 95% CI high | p | OR | 95% CI low | 95% CI high | p | ||
| Age | <46 | 1(Reference) | 0.935 | ||||||
| ≥46 | 0.971 | 0.473 | 1.991 | ||||||
| Marital status | Married | 1(Reference) | 0.668 | ||||||
| Unmarried + Divorce + Widowed | 1.277 | 0.410 | 3.974 | ||||||
| Occupation | Mental worker | 1(Reference) | 0.597 | ||||||
| Manual worker + Others | 1.295 | 0.491 | 3.425 | ||||||
| Weight | <60 | 1(Reference) | 0.372 | ||||||
| ≥60 | 1.389 | 0.677 | 2.875 | ||||||
| Height | <1.61 | 1(Reference) | 0.837 | ||||||
| ≥1.61 | 0.927 | 0.451 | 1.905 | ||||||
| BMI | <22.83 | 1(Reference) | 0.082 | ||||||
| ≥22.83 | 1.906 | 0.926 | 3.980 | ||||||
| LDH | <158.10 | 1(Reference) | 0.935 | ||||||
| ≥158.10 | 0.971 | 0.473 | 1.991 | ||||||
| ALB | <44.40 | 1(Reference) | 0.168 | ||||||
| ≥44.40 | 1.662 | 0.810 | 3.453 | ||||||
| CRP | <0.02 | 1(Reference) | 0.627 | ||||||
| ≥0.02 | 0.837 | 0.406 | 1.715 | ||||||
| CHOL | <4.83 | 1(Reference) | 0.776 | ||||||
| ≥4.83 | 1.110 | 0.541 | 2.280 | ||||||
| FIB | <2.73 | 1(Reference) | 0.329 | ||||||
| ≥2.73 | 0.699 | 0.338 | 1.433 | ||||||
| W | <5.68 | 1(Reference) | 0.516 | ||||||
| ≥5.68 | 1.269 | 0.619 | 2.614 | ||||||
| R | <4.45 | 1(Reference) | 0.181 | ||||||
| ≥4.45 | 0.611 | 0.294 | 1.253 | ||||||
| Hb | <133 | 1(Reference) | 0.036 | 1(Reference) | 0.035 | ||||
| ≥133 | 0.457 | 0.217 | 0.943 | 0.401 | 0.168 | 0.926 | |||
| N | <3.56 | 1(Reference) | 0.966 | ||||||
| ≥3.56 | 0.985 | 0.480 | 2.022 | ||||||
| L | <1.69 | 1(Reference) | 0.904 | ||||||
| ≥1.69 | 1.045 | 0.510 | 2.147 | ||||||
| M | <0.30 | 1(Reference) | 0.144 | ||||||
| ≥0.30 | 1.719 | 0.834 | 3.591 | ||||||
| P | <252 | 1(Reference) | 0.776 | ||||||
| ≥252 | 1.110 | 0.541 | 2.280 | ||||||
| Type of surgery | Mastectomy | 1(Reference) | 0.019 | 1(Reference) | 0.040 | ||||
| Breast-conserving surgery | 0.278 | 0.086 | 0.759 | 0.273 | 0.071 | 0.883 | |||
| Tumor size | <2 | 1(Reference) | 0.133 | ||||||
| ≥2 | 1.752 | 0.848 | 3.676 | ||||||
| Histologic type | Ductal | 1(Reference) | 0.556 | ||||||
| Lobular + Others | 1.321 | 0.529 | 3.441 | ||||||
| Histologic grade | 0+I | 1(Reference) | 0.376 | ||||||
| II+III | 1.414 | 0.661 | 3.079 | ||||||
| Pathological T stage | Tis/T0 | 1(Reference) | 0.011 | 1(Reference) | 0.039 | ||||
| T1+T2+T3 | 2.809 | 1.278 | 6.363 | 6.684 | 1.155 | 44.961 | |||
| Pathological N stage | 1 | 1(Reference) | 0.533 | ||||||
| 2 | 1.276 | 0.592 | 2.752 | ||||||
| Pathological TNM stage | 1 | 1(Reference) | 0.287 | ||||||
| 2 | 1.481 | 0.720 | 3.070 | ||||||
| TLN | <7 | 1(Reference) | 0.394 | ||||||
| ≥7 | 1.367 | 0.667 | 2.824 | ||||||
| PLN | <1 | 1(Reference) | 0.816 | ||||||
| ≥1 | 1.095 | 0.506 | 2.358 | ||||||
| Molecular subtype | Luminal A + Luminal B (HER2+) + Luminal B (HER2-) | 1(Reference) | 0.181 | ||||||
| HER2 enriched + Triple negative | 2.667 | 0.668 | 13.140 | ||||||
| ER status | Negative | 1(Reference) | 0.830 | ||||||
| Positive | 1.098 | 0.470 | 2.618 | ||||||
| PR status | Negative | 1(Reference) | 0.745 | ||||||
| Positive | 1.162 | 0.473 | 2.939 | ||||||
| HER2 | Negative | 1(Reference) | 0.304 | ||||||
| Positive | 1.629 | 0.643 | 4.203 | ||||||
| Ki-67 | Negative | 1(Reference) | 0.099 | ||||||
| Positive | 1.929 | 0.894 | 4.290 | ||||||
| AR | Negative | 1(Reference) | 0.095 | ||||||
| Positive | 2.128 | 0.897 | 5.372 | ||||||
| CK5/6 | Negative | 1(Reference) | 0.388 | ||||||
| Positive | 0.477 | 0.066 | 2.313 | ||||||
| E-cad | Negative | 1(Reference) | 0.292 | ||||||
| Positive | 1.542 | 0.696 | 3.518 | ||||||
| EGFR | Negative | 1(Reference) | 0.406 | ||||||
| Positive | 0.636 | 0.206 | 1.803 | ||||||
| P53 | Negative | 1(Reference) | 0.391 | ||||||
| Positive | 1.378 | 0.665 | 2.892 | ||||||
| TOP2A | Negative | 1(Reference) | 0.039 | 1(Reference) | 0.226 | ||||
| Positive | 2.188 | 1.051 | 4.656 | 1.945 | 0.672 | 5.920 | |||
| Lymph vessel invasion | Negative | 1(Reference) | 0.931 | ||||||
| Positive | 1.042 | 0.404 | 2.638 | ||||||
| Neural invasion | Negative | 1(Reference) | 0.758 | ||||||
| Positive | 0.849 | 0.288 | 2.382 | ||||||
| Healthy lower arm circumference | <19 | 1(Reference) | 0.655 | ||||||
| ≥19 | 1.178 | 0.575 | 2.423 | ||||||
| Healthy upper arm circumference | <26 | 1(Reference) | 0.329 | ||||||
| ≥26 | 1.431 | 0.698 | 2.955 | ||||||
| Affected side lower arm circumference | <19 | 1(Reference) | 0.966 | ||||||
| ≥19 | 1.016 | 0.495 | 2.085 | ||||||
| Affected side upper arm circumference | <26 | 1(Reference) | 0.368 | ||||||
| ≥26 | 1.393 | 0.678 | 2.879 | ||||||
| Chest wall drainage tube | <13 | 1(Reference) | 0.000 | 1(Reference) | 0.000 | ||||
| ≥13 | 92.188 | 29.083 | 374.069 | 127.427 | 25.938 | 1139.723 | |||
| Axillary drainage tube | <13 | 1(Reference) | 0.000 | 1(Reference) | 0.480 | ||||
| ≥13 | 5.298 | 2.441 | 12.090 | 1.872 | 0.311 | 11.822 | |||
| NLR | <1.86 | 1(Reference) | 0.370 | ||||||
| ≥1.86 | 0.711 | 0.336 | 1.498 | ||||||
| dNLR | <1.48 | 1(Reference) | 0.271 | ||||||
| ≥1.48 | 0.659 | 0.312 | 1.383 | ||||||
| MLR | <0.12 | 1(Reference) | 0.745 | ||||||
| ≥0.12 | 1.162 | 0.473 | 2.939 | ||||||
| PLR | <159.3 | 1(Reference) | 0.317 | ||||||
| ≥159.3 | 0.681 | 0.317 | 1.438 | ||||||
| SIRI | <0.63 | 1(Reference) | 0.181 | ||||||
| ≥0.63 | 1.638 | 0.798 | 3.398 | ||||||
| SII | <262.5 | 1(Reference) | 0.124 | ||||||
| ≥262.5 | 0.403 | 0.117 | 1.248 | ||||||
| PNI | <55.58 | 1(Reference) | 0.082 | ||||||
| ≥55.58 | 2.055 | 0.918 | 4.698 | ||||||
| NRI | <109.7 | 1(Reference) | 0.013 | 1(Reference) | 0.025 | ||||
| ≥109.7 | 2.716 | 1.256 | 6.116 | 2.837 | 1.164 | 7.292 | |||
| AFR | <17.36 | 1(Reference) | 0.068 | ||||||
| ≥17.36 | 2.021 | 0.954 | 4.345 | ||||||
| HALP | <34.87 | 1(Reference) | 0.317 | ||||||
| ≥34.87 | 1.469 | 0.695 | 3.159 | ||||||
| CONUT | <1 | 1(Reference) | 0.508 | ||||||
| ≥1 | 1.277 | 0.619 | 2.645 | ||||||
| BIPI | Good | 1(Reference) | 0.481 | ||||||
| Intermediate + Poor | 1.514 | 0.473 | 4.990 | ||||||
Abbreviations: BMI, body mass index; LDH, lactic dehydrogenase; ALB, albumin; CRP, C-reactive protein; CHOL, cholesterol; FIB, fibrinogen; W, white blood cell; R, red blood cell; Hb, hemoglobin; N, neutrophils; L, lymphocyte; M, monocyte; P, platelet; TLN, Total lymph nodes; PLN, Positive lymph nodes; ER, estrogen receptor; PR, progesterone receptor; HER2, Human Epidermal Growth Factor Receptor 2; AR, androgen receptor; CK5/6, Cytokeratin 5/6; E-cad, E-cadherin; EGFR, Epidermal Growth Factor Receptor; TOP2A, topoisomerase 2A; NLR, neutrophil-to-lymphocyte ratio; dNLR, derived neutrophil-to-lymphocyte ratio; MLR, monocyte-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; SIRI, systemic inflammation response index; SII, systemic immune-inflammation index; PNI, prognostic nutritional index; NRI, nutritional risk index; AFR, albumin-to-fibrinogen ratio; HALP, hemoglobin × albumin × lymphocyte / platelet; CONUT, controlling nutritional status; BIPI, breast immune prognostic index.