Table 2.

Predictors of overall survival after matching

	Univariable					Multivariable
Characteristic	N	Event N	HR1	95% CI1	p-value	N	Event N	HR1	95% CI1	p-value
Gender
Male	373	216	–	–		373	216	–	–
Female	44	28	1.02	0.68, 1.51	0.935	44	28	1.25	0.81, 1.91	0.312
Age	417	244	1.00	0.99, 1.01	0.948	417	244	1.00	0.99, 1.01	0.745
BCLC
B	288	154	–	–		288	154	–	–
C	129	90	1.74	1.34, 2.27	< 0.001	129	90	1.25	0.72, 2.17	0.428
ECOG
0	342	199	–	–		342	199	–	–
1	75	45	1.11	0.80, 1.53	0.546	75	45	1.09	0.78, 1.54	0.608
Tumor number
≥ 3 nodules	326	189	–	–		326	189	–	–
< 3 nodules	91	55	1.43	1.06, 1.93	0.020	91	55	1.43	1.03, 1.98	0.031
Tumor Size
< 7	139	83	–	–		139	83	–	–
≥ 7	278	161	1.13	0.86, 1.47	0.385	278	161	1.01	0.76, 1.34	0.962
Extrahepatic metastasis
Absent	339	187	–	–		339	187	–	–
Present	78	57	1.64	1.22, 2.21	0.001	78	57	1.49	1.00, 2.21	0.051
PVTT
Absent	322	178	–	–		322	178	–	–
Present	95	66	1.63	1.23, 2.17	< 0.001	95	66	1.15	0.70, 1.91	0.579
AFP
< 400	312	178	–	–		312	178	–	–
≥ 400	105	66	1.32	1.00, 1.76	0.053	105	66	1.17	0.87, 1.59	0.302
Child Pugh
A	354	208	–	–		354	208	–	–
B	63	36	0.93	0.65, 1.32	0.682	63	36	0.97	0.67, 1.41	0.881
Ascites
Absent	329	189	–	–		329	189	–	–
Present	88	55	1.14	0.84, 1.53	0.410	88	55	1.07	0.78, 1.48	0.656
HBVDNA
Positive	168	103	–	–		168	103	–	–
Negative	249	141	0.76	0.59, 0.99	0.038	249	141	0.80	0.60, 1.05	0.112
HCVRNA
Negative	401	235	–	–		401	235	–	–
Positive	16	9	1.24	0.64, 2.42	0.523	16	9	1.22	0.61, 2.47	0.571
Group
TACE	278	171	–	–		278	171	–	–
TACE + TKIs + ICIs	139	73	0.72	0.54, 0.95	0.022	139	73	0.73	0.55, 0.97	0.032

¹HR = Hazard Ratio, CI = Confidence Interval