Fig. 5. Humanized NSG-SGM3 mice developed antibody responses against phage DS6A.

ELISA was performed to determine the phage DS6A-specific human IgA (A), IgM (B), and IgG (C) titers in sera of the humanized mice infected with H37Rv and treated with phage DS6A or PBS buffer control. The experiment was repeated once, and the results from one experiment with five mice each group are shown. All the statistics are shown as mean ± SEM. Unpaired Student’s T-test was used to analyze the differences between groups. Statistical significance was defined as *P ≤ 0.05, **P ≤ 0.01, and ***P ≤ 0.001.