Table 1.
Baseline patient characteristics of individuals with ischemic stroke in the derivation cohort
| Characteristics | Total (n = 45,162) | Adverse Outcome (−) (n = 44,640) |
Adverse Outcome (+) (n = 522) |
P-value |
|---|---|---|---|---|
| Patient status | ||||
| Age, years | 60.4 ± 14.4 | 60.3 ± 14.3 | 72.1 ± 14.8 | < 0.001 |
| Sex male, n (%) | 27,690 (61.31%) | 27,329 (61.22%) | 361 (69.16%) | < 0.001 |
| Smoker, n (%) | 13,873 (30.72%) | 13,692 (30.67%) | 181 (34.67%) | 0.049 |
| Drinker, n (%) | 9046 (20.03%) | 8926 (20.00%) | 120 (22.99%) | 0.089 |
| SBP, mmHg | 133.5 ± 21.8 | 133.5 ± 21.7 | 126.1 ± 24.0 | < 0.001 |
| DBP, mmHg | 81.0 ± 13.0 | 81.1 ± 13.0 | 73.4 ± 15.2 | < 0.001 |
| Fat indicators | ||||
| TC, mmol/L | 4.41 ± 1.09 | 4.41 ± 1.08 | 4.77 ± 1.26 | < 0.001 |
| TG, mmol/L | 1.76 ± 1.25 | 1.75 ± 1.24 | 2.11 ± 1.61 | < 0.001 |
| HDL, mmol/L | 1.12 ± 0.30 | 1.12 ± 0.30 | 1.18 ± 0.37 | < 0.001 |
| BFP, % | 30.7 ± 5.8 | 30.6 ± 5.8 | 32.5 ± 5.8 | < 0.001 |
| BMI, kg/m2 | 0.291 | |||
| < 18.5 | 580 (1.28%) | 572 (1.28%) | 8 (1.53%) | |
| 18.5–24 | 20,579 (45.57%) | 20,325 (45.53%) | 254 (48.66%) | |
| ≥ 24 | 24,003 (53.15%) | 23,743 (53.19%) | 260 (49.81%) | |
| Comorbidities | ||||
| Diabetes, n (%) | 10,885 (24.10%) | 10,705 (23.98%) | 180 (34.48%) | < 0.001 |
| Hypertension, n (%) | 24,496 (54.24%) | 24,146 (54.09%) | 350 (67.05%) | < 0.001 |
| CHD, n (%) | 13,173 (29.17%) | 12,827 (28.73%) | 346 (66.28%) | < 0.001 |
| CKD, n (%) | 4477 (9.91%) | 4306 (9.65%) | 171 (32.76%) | < 0.001 |
| CRD, n (%) | 18,171 (40.24%) | 17,754 (39.77%) | 417 (79.89%) | < 0.001 |
| Treatment | ||||
| Aspirin use, n (%) | 17,130 (40.15%) | 16,940 (37.95%) | 190 (36.40%) | 0.380 |
| Clopidogrel use, n (%) | 13,259 (31.08%) | 13,095 (29.33%) | 164 (31.42%) | 0.352 |
| Thrombolytic, n (%) | 462 (1.08%) | 446 (1.00%) | 16 (3.07%) | < 0.001 |
| Insulin use, n (%) | 7080 (16.59%) | 6827 (15.29%) | 253 (48.47%) | < 0.001 |
| Antihypertensive use, n (%) | 17,410 (38.55%) | 17,190 (38.51%) | 220 (42.15%) | 0.090 |
| Statin use, n (%) | 20,278 (47.53%) | 20,025 (44.86%) | 253 (48.47%) | 0.129 |
| Oxygen therapy, n (%) | 12,799 (28.34%) | 12,563 (28.14%) | 236 (45.21%) | < 0.001 |
BFP Body fat percentage, BMI Body Mass Index, CHD Chronic cardiac disease, CKD Chronic Kidney Disease, CRD Chronic respiratory disease, DBP diastolic blood pressure, HDL High-Density Lipoprotein, SBP Systolic blood pressure, TC Total Cholesterol, TG Triglyceride
The demographic and clinical data were presented as column percentages (%)