Table 2.

median iPFS according to local treatment modalities of BM.

Local treatment of BM	iPFS (months)	p
Surgery	25.5 (2.5–48.4)	S vs WBRT: 0.01
SRS	23.4 (18.1–28.7)	SRS vs WBRT: 0.008
1–3 BM	24.8 (18.8–30.7)	0.08
≥ 4 BM	14.2 (4.8–23.6)
WBRT	13 (7–19)
1–3 BM	20.6 (16.3–25)	0.01
≥ 4 BM	9.5 (6–13)
Follow-up	19 (11.3–26.8)

BM brain metastasis, S surgery, SRS stereotactic radiosurgery, WBRT whole-brain radiotherapy.