Table 3:
Expression of SAR1A under the control of Sar1b locus rescues the lethality in Sar1b null mice
| Mating Genotype Expected |
Sar1b+/a X Sar1b+/a |
p-value (χ2 test) | ||
|---|---|---|---|---|
| Sar1b+/+ 25% | Sar1b+/a 50% | Sar1ba/a 25% | ||
|
| ||||
| Weaning | 80 (30%) | 148 (55%) | 43 (15%) | 0.002 |
|
| ||||
| Mating Genotype Expected |
Sar1b+/a X Sar1ba/a
|
|||
| Sar1b+/a 50% | Sar1ba/a 50% | |||
|
| ||||
| Weaning | 23 (52%) | 21 (48%) | 0.763 | |