Extended Data Figure 5 |. Neuroinflammatory biomarkers in plasma.

The MSD platform was used to detect the indicated proteins in plasma of participants at baseline (PRE) and after 24 weeks of 3TC treatment (POST). Normality testing was based on the POST-PRE difference for each target. N=12. Significant P value is noted; all other P values are provided in Table 4. P values are based on two-sided paired sample t-test (normal distribution) or Wilcoxon matched-pairs signed rank test (non-normal distribution).