Table 5.
Treated & control Group of mice |
Dose of treatment | Mean ± SD | Treatment efficacy | The infectivity of the cyst | |
---|---|---|---|---|---|
Group (I) | Infected Treated with Ag-NPs at 3rd, 4th and 5th dpi | 21.5 mg/kg | 45 ± 6.7* | 86.61% | No |
21.5 mg/kg + MM 5 mg/kg | 36.8 ± 5.45* | 89.07% | No | ||
Albendazole 50 mg/kg | 37.6 ± 4.97* | 88.84% | No | ||
Infected untreated mice | 336.8 ± 13.84 | - | No | ||
Group (II) | Infected Treated with Ag-NPs at 8th, 9th and 10th dpi | 21.5 mg/kg | 119.6 ± 7.16* | 70.77% | Dead |
21.5 mg/kg + MM 5 mg/kg | 105.2 ± 6.43* | 74.29% | Dead | ||
Albendazole 50 mg/kg | 111.4 ± 5.94* | 72.78% | Dead | ||
Infected untreated mice | 409.2 ± 25.59 | - | Infective | ||
Group (III) | Infected Treated with Ag-NPs at 33rd, 34th and 35th dpi | 21.5 mg/kg | 255.2 ± 28.33* | 55.73% | Not infective |
21.5 mg/kg + MM 5 mg/kg | 243.6 ± 16.52* | 57.81% | Not infective | ||
Albendazole 50 mg/kg | 268.8 ± 30.87* | 53.47% | Infective | ||
Infected untreated mice | 576.4 ± 42.16 | - | Infective | ||
Group (IV) | Control non-infected mice | 0 | 0 | No |
*P-value < 0.001 statistically significant.