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. 2024 Mar 11;14:5847. doi: 10.1038/s41598-024-56570-9

Table 2.

Patient characteristics before and after IPTW compared between the thienopyridine and aspirin groups.

Parameter Total Unweighted study cohort Weighted study cohort
Thienopyridine group vs Aspirin group SD Thienopyridine group vs Aspirin group SD
Patients, no 520 147 373
Median age, years (IQR) 71 (68–74) 71 (67–74) 71 (68–74) − 0.014 71 (67–75) 71 (68–74) − 0.023
ASA PS, n (%)
 1 63 (12) 17 (11) 46 (12) 0.257 13% 12% 0.013
 2 358 (69) 91 (62) 267 (72) 67% 69%
 3, or more 99 (19) 39 (27) 60 (16) 20% 19%
BMI ≧ 25 kg/m2, n (%) 204 (39) 50 (34) 154 (41) − 0.151 38% 39% − 0.015
KDIGO CKD grade (eGFR), n (%)
 Grade 1, or 2 (60 mL/min/1.73 m2, or more) 333 (64) 89 (61) 244 (65) 0.101 65% 64% − 0.020
 Grade 3a, or 3b (30–59 mL/min/1.73 m2) 172 (33) 51 (35) 121 (32) 32% 33%
 Grade 4, or 5 (29 mL/min/1.73 m2, or less) 15 (2.9) 7 (4.7) 8 (2.1) 3.4% 3.1%
NCCN risk classification group, n (%)
 Low 15 (2.9) 4 (2.9) 11 (3.0) 0.074 2.6% 3.0% 0.002
 Intermediate 257 (49) 69 (47) 188 (40) 49% 49%
 High, or more 248 (48) 74 (50) 174 (47) 48% 48%
Pelvic lymph node dissection, n (%)
 None 269 (51) 75 (51) 194 (52) − 0.126 52% 53% − 0.040
 Limited 144 (28) 47 (32) 97 (26) 29% 27%
 Extended 107 (21) 25 (17) 82 (22) 19% 20%
Neurovascular bundle preservation, n (%) 154 (30) 46 (31) 108 (29) 0.051 29% 29% 0.040
Preoperative hormonal therapy, n (%) 132 (25) 32 (22) 100 (27) − 0.118 27% 26% 0.024
Perioperative continuation of antiplatelets, n (%) 133 (26) 25 (17) 108 (29) − 0.287 24% 26% − 0.036

ASA PS, American Society of Anesthesiologists physical status classification; BMI, body mass index; CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; IPTW, inverse probability of treatment weighting; IQR, interquartile range; KDIGO, kidney disease improving global outcomes; NCCN, National Comprehensive Cancer Network; SD, Standardized difference.

Significant values are in bold.