Table 2.
Assessment of efficacy in patients received radical resection
| Time from the end of radiotherapy to surgery [median (range)] days | 61 (43–84) |
| R0 resection (yes/no) | 46 (100.0%) / 0 (0.0%) |
| Anal-preserving (yes/no) | 41 (89.1%) / 5 (10.9%) |
| Defunctioning ileostomy | 13 (28.3%) |
| Colostomy | 5 (10.9%) |
| No stomas | 28 (60.9%) |
| AJCC tumor regression grade (0/1/2/3) | 20 (43.5%) / 15 (32.6%) / 9 (19.6%) / 2 (4.3%) |
| ypT category (ypT0/ypT1/ypT2/ypT3/ypT4) | 21 (45.7%) / 4 (8.7%) / 4 (8.7%) / 16 (34.8%) / 1 (2.2%) |
| ypN category (ypN0/ypN1/ypN2) | 41 (89.1%) / 4 (8.7%) / 1 (2.2%) |
| MRI tumor regression grade (0/1/2/3) | 18 (39.1%) / 22 (47.8%) / 5 (10.9) / 1 (2.2%) |
| ycT category (ycT0/ycT1/ycT2/ycT3/ycT4) | 18 (39.1%) / 5 (10.9) / 7 (15.2%) / 14 (30.4%) / 2 (4.3%) |
| ycN category (ycN0/ycN1/ycN2) | 40 (87.0%) / 4 (8.7%) / 2 (4.3%) |
| Clinical evaluation through RECIST | |
| CR | 18 (39.1%) |
| PR | 18 (39.1%) |
| SD | 10 (21.7%) |
| PD | 0 (0%) |
| ORR | 35 (76.1%) |
| Neoadjuvant rectal score [median (range)] | 14.98 (0.94–70.34) |
AJCC American Joint Committee on Cancer, MRI magnetic resonance imaging, RECIST Response Evaluation Criteria in Solid Tumors, CR complete response, PR partial response, SD stable disease, PD progressive disease, ORR objective response rate