Table 3.
The comparation of clinical characteristics between baseline and 6 months in different risk groups.
| Characteristics | Low (n = 22) | Intermediate‐low (n = 35) | Intermediate‐high (n = 91) | High (n = 44) | ||||
|---|---|---|---|---|---|---|---|---|
| Baseline | Follow‐up | Baseline | Follow‐up | Baseline | Follow‐up | Baseline | Follow‐up | |
| WHO‐FC I/II/III/IV, n | 0/22/0/0 | 3/19/0/0 | 0/12/23/0 | 2/16/17/0* | 0/5/78/8 | 5/24/52/5*** | 0/1/25/18 | 1/3/27/12** |
| 6MWD, m | 498.9 ± 73.8 | 511.2 ± 80.8 | 395.9 ± 81.1 | 421.1±106.1 | 322.8 ± 101.1 | 365.5 ± 130.0* | 102.0 ± 57.3 | 248.7±143.3*** |
| NT‐proBNP, pg/mL | 97.9 (29.3–239.6) | 106.7 (22.1–229.9) | 334.8 (106.1–770.5) | 201.0 (110.7–620.0) | 2009.0 (1132.5–3842.5) | 1473.5 (442.5–3159.0)** | 2940.5 (1759.3–5868.0) | 1770.0 (884.2–5677.5) |
| PASP, mmHg | 71.8 ± 19.7 | 72.7 ± 26.1 | 87.1 ± 35.5 | 84.7 ± 25.1 | 100.6 ± 30.3 | 94.3 ± 32.7 | 97.3 ± 22.6 | 90.7 ± 27.4 |
| RA area, cm2 | 22.6 ± 6.0 | 19.8 ± 6.0* | 20.8 ± 8.0 | 20.9 ± 9.6 | 30.6 ± 15.2 | 28.6 ± 16.0 | 36.4 ± 20.6 | 37.5 ± 23.5 |
| RAP, mmHg | 13.3 ± 14.6 | 7.5 ± 3.8 | 10.0 ± 5.2 | 8.3 ± 4.9 | 11.1 ± 5.1 | 10.5 ± 4.9 | 16.1 ± 17.9 | 8.9 ± 6.1 |
| RV diameter, cm | 5.2 ± 1.7 | 5.1 ± 1.4 | 4.8 ± 1.5 | 4.7 ± 1.4 | 5.2 ± 1.3 | 5.1 ± 1.4 | 5.4 ± 0.8 | 5.0 ± 1.0* |
| Sm, cm/s | 10.3 ± 3.4 | 9.9 ± 3.4 | 11.5 ± 2.0 | 11.4 ± 1.8 | 10.1 ± 2.7 | 10.6 ± 2.2 | 10.5 ± 3.3 | 11.0 ± 2.0 |
| LVEDD, mm | 39.4 ± 4.0 | 41.0 ± 4.8 | 38.9 ± 8.5 | 39.4 ± 6.2 | 32.6 ± 6.7 | 35.3 ± 6.5** | 35.4 ± 5.9 | 34.9 ± 6.6 |
| EI | 1.8 ± 0.8 | 1.7 ± 0.7* | 1.8 ± 0.8 | 1.7 ± 0.7 | 1.9 ± 0.6 | 1.8 ± 0.6** | 1.9 ± 0.6 | 1.9 ± 0.6 |
| TAPSE, cm | 1.8 ± 0.4 | 1.8 ± 0.2 | 1.9 ± 0.5 | 2.0 ± 0.5* | 1.5 ± 0.4 | 1.6 ± 0.4* | 1.5 ± 0.3 | 1.6 ± 0.3 |
| PE, % | 10 | 6.7 | 21.4 | 15.8 | 50.6 | 31.9* | 43.6 | 23.1 |
Note: Data are presented as n (%), mean ± SD, and interquartile range. *p < 0.05, **p < 0.01, ***p < 0.001.
Abbreviations: 6MWD, 6‐min walking distance; EI, eccentricity index; LVEDD, left ventricular end‐diastolic dimension; NT‐proBNP, N‐terminal pro‐brain natriuretic peptide; PASP, pulmonary arterial systolic pressure; PE, pericardial effusion; RA area, right atrium area; RAP, right atrial pressure; RV, right ventricle; Sm, peak systolic velocity of tricuspid annulus; TAPSE, tricuspid annular plane systolic excursion; WHO‐FC, World Health Organization functional classification.