Table II.

U nivariate analyses of factors associated with AKI after surgery for congenital heart disease.

Variable		Ordinal AKI outcome			Dichotomous AKI outcome
		OR	95% CI	P-value	OR	95% CI	P-value
Age, years		0.92	[0.90–0.94]	<.001	0.92	[0.91 –0.94]	< .001
BSA (m2)		0.35	[0.28–0.44]	<.001	0.36	[0.29–0.46]	< .001
Male Sex		1.19	[1.00–1.41]	.056	1.22	[1.02–1.47]	.027
Genetic Syndrome STAT Score		1.74	[1.42–2.12]	<.001	1.64	[1.32–2.02]	< .001
STAT Score 1		1.00	Reference	-	1.00	Reference	-
STAT Score 2		1.67	[1.29–2.17]	<.001	1.67	[1.28–2.17]	< .001
STAT Score 3		3.32	[2.47–4.46]	<.001	3.29	[2.43–4.45]	< .001
STAT Score 4		4.01	[3.13–5.14]	<.001	4.13	[3.19–5.35]	< .001
STAT Score 5		8.19	[5.91–11.36]	<.001	10.58	[7.12–15.73]	< .001
CPB time (per ten min)		1.06	[1.05–1.07]	<.001	1.07	[1.05–1.08]	< .001
Aortic Cross Clamp time (per ten min)		1.07	[1.05–1.10]	<.001	1.07	[1.05–1.10]	< .001
Nephrotoxin Risk score		1.23	[1.16–1.30]	<.001	1.23	[1.16–1.31]	< .001
rs429358	APOE	1.06	[0.83–1.35]	.635	1.06	[0.82–1.37]	.655
rs7412	APOE	1.05	[0.87–1.26]	.637	1.08	[0.89–1.31]	.455
rs5186	AGTR1	0.99	[0.83–1.18]	.953	1.00	[0.84–1.20]	.973
rs2070744	NOS3	0.80	[0.67–0.95]	.012	0.75	[0.62–0.90]	.002
rs1800796	IL6	1.00	[0.79–1.27]	.986	0.99	[0.77–1.26]	.927
rs1800629	TNF	0.92	[0.75–1.12]	.392	0.89	[0.73–1.09]	.278

Abbreviations: AKI, acute kidney injury; BSA, body surface area; CPB, cardiopulmonary bypass; OR, Odds Ratio; STAT, Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery.