Table 4.
Literature review on ear drops
| Study | Participants | Intervention | Outcomes |
|---|---|---|---|
| Carr et al. ( 10 ) | 67 | 10% aqueous sodium bicarbonate | Extent of wax clearance by change in score for cerumen |
| Dummer et al. (11) | 50 | choline salicylate and polyoxypropylene glycol condensate (Audax) | Amount of wax |
| Jaffe et al. (12) | 106 | phenazone and sodium carbonate (Otocerol) | Degree of wax clearance |
| Keane et al. (5) | 97 | arachis oil 57.3%, chlorobutanol 5%, paradichlorobenzene 2%) (Cerumol) | Proportion of patients with complete clearance of wax |
| Lyndon et al. (13) | 35 | choline salicylate 20%, ethylene oxide-polyoxypropylene glycol, glycol and glycerol (Audax) | Proportion of participants with complete clearance of wax |
| Meehan et al. (14) | 48 | docusate sodium (Colace) | Extent of wax clearance |
| Oron et al. (15) | 38 | carbamide peroxide and anhydrous glycerin (Auro), chlorobutanol, arachis oil and dichlorobenzene (Cerumol), and squalane, spiramint oil and paraffin (CleanEars) |
Extent of wax clearance |
| Singer et al. (16) | 50 | docusate sodium (Colace), and triethanolamine polypeptide (Cerumenex) |
Proportion of patients with complete clearance of wax |
| Vanlierde et al. (17) | 40 | almond oil | Reduction in wax from grade 3 or 4 to grade 2 |
| Whatley et al. (18) | 92 | docusate sodium (Colace), triethanolamine polypeptide (Ceruminex), and saline |
Proportion of ears with complete visualization of tympanic membrane |