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Footprinting of the far upstream boundary of the differentially methylated sequences. (A) Upper strand, the J primer set used for LMPCR; (B) lower strand, the I primer set used. Filled and open squares indicate increases and decreases, respectively, in DMS reactivity in PG ES cells; dashed lines indicate the regions with the highest DNase I sensitivity. For other details, see the legend to Fig. 2.
