Figure 2.

PaNDA-based 13C,15N-labeleing of ssDNA for 15-bp DNA and the 22-nt telomere repeat DNA G-quadruplex (Tel22). (A) Comparison of the spectra recorded for the 15-bp DNA duplex in which only one strand is 13C,15N-labeled by PaNDA (red) and for the same DNA in which both strands are 13C/15N-labeled by PCR (black). (B) 1H-15N and 1H-13C HSQC spectra recorded for Tel22 in the pH 7.4 phosphate buffers with either 100 mM NaCl or 100 mM KCl.