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. 2024 Jan 16;11:1324898. doi: 10.3389/fcell.2023.1324898

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Copyright © 2024 Nakahara, Kouro, Motoyama, Miura, Fujita, Igarashi, Higashijima, Matsuo, Himuro, Wei, Horaguchi, Tsuji, Mano, Komahashi, Saito, Azuma and Sasada.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differences in plasma IL-6 and sIL-6R levels according to the IL-6 (−634G>C) or IL-6R (48892A>C) polymorphism. Plasma IL-6 and sIL-6R levels were compared among three subgroups according to the IL-6 (−634G>C) (A) or IL-6R (48892A>C) (B) polymorphism by Student’s t-test. Data are presented as box plots. The bottom and top of the box represent the first and third quartiles, and the band and “X” inside the box correspond to the median and mean, respectively. Whiskers indicate the variability outside the upper and lower quartiles. Outliers are shown as individual points. *p < 0.001. NS, not significant (p > 0.05).