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Nanotechnology may help increasing RNAi efficiency in major pests. Nanoformulations of dsRNA such as dsRNA, polyphenol (−)-epigallocatechin-3-O-gallate (EGCG) and poly-l-lysine (PLL) protect dsRNA from degradation by dsRNases, improve uptake, intracellular transport and endosomal escape of dsRNA resulting in increased RNAi efficiency.
