Table 4.
Diagnostic performance of LAM in combination of 1 other method in PTB.
| Methods | Results | CRS | Sensitivity | Increment | Specificity | PPV | NPV | Kappa | |
|---|---|---|---|---|---|---|---|---|---|
| PTB | Non-TB | ||||||||
| LAM + smear | positive | 101 | 0 | 58.38%# | 46.24% | 100.00% | 100.00% | 33.94% | 0.331 |
| negative | 72 | 37 | |||||||
| LAM + culture | positive | 110 | 0 | 63.58%# | 27.17% | 100.00% | 100.00% | 37.00% | 0.381 |
| negative | 63 | 37 | |||||||
| LAM + RNA | positive | 105 | 0 | 60.69%# | 34.10% | 100.00% | 100.00% | 35.24% | 0.352 |
| negative | 68 | 37 | |||||||
| LAM + Xpert | positive | 119 | 0 | 68.79%*# | 24.28% | 100.00% | 100.00% | 40.66% | 0.437 |
| negative | 54 | 37 | |||||||
CRS, composite reference standard; PTB, pulmonary tuberculosis; PPV, positive predictive value; NPV, negative predictive value; RNA, ribonucleic acid; TB, tuberculosis; LAM, lipoarabinomannan; *p < 0.05, Compared to LAM; #p < 0.05, compared to single detection.