Table 2.

Comparison of histopathological data of cases according to tumor subtype (n = 72)

	Adenocarcinoma (n = 33)			SCC (n = 29)			NSCLC (n = 10)
	Control group (n = 19)	Study group (n = 14)	P value	Control group (n = 18)	Study group (n = 11)	P value	Control group (n = 2)	Study group (n = 8)	P value
Tumor Diameter (mm)   (Min-Max)	35 (15–80)	40 (12–73)	0.956	35.5 (13–65)	40 (7–55)	0.421	30 (15–45)	36.5 (5–70)	0.711
Lymph node metastasis, N (%)	10 (52.6)	8 (57.1)	0.797	5 (27.8)	4 (36.4)	0.943	0 (0.0)	2 (25.0)	0.429
Pleural invasion, N (%)	3 (15.8)	2 (14.3)	0.905	2 (11.1)	0 (0.0)	0.696	1 (50.0)	3 (37.5)	0.747
Lymphovascular invasion, N (%)	6 (31.6)	3 (21.4)	0.801	3 (16.7)	0 (0.0)	0.423	0 (0.0)	2 (25.0)	0.429
Fibrosis, N (%)	15 (78.9)	12 (85.7)	0.967	7 (38.9)	11 (100.0)	0.0038	1 (50.0)	5 (62.5)	0.747
Necrosis, N (%)	11 (57.9)	6 (42.9)	0.616	13 (72.2)	6 (54.5)	0.569	1 (50.0)	2 (25.0)	0.490
Foreign body reaction, N (%)	0 (0.0)	6 (42.9)	0.007	0 (0.0)	3 (27.3)	0.087	0 (0.0)	2 (25.0)	0.429
Degree of inflammation,
N (%)
Mild	6 (31.6)	3 (21.4)		9 (50.0)	6 (54.5)		1 (50.0)	2 (25.0)
Moderate	11 (57.9)	1 (7.1)	0.0008	8 (44.4)	3 (27.3)	0.447	1 (50.0)	3 (37.5)	0.564
Severe	2 (10.5)	10 (71.4)		1 (5.6)	2 (18.2)		0 (0.0)	3 (37.5)
CD4/CD8 ratio
(Min-Max)
Intratumoral	1.13 (0.00-7.13)	0.74 (0.13–2.67)	0.469	1.52 (0.04–5.60)	0.77 (0.11-2.00)	0.0139	1.2 (0.33–2.07)	0.67 (0.22–2.05)	0.794
Peritumoral	1.47 (0.03–11.42)	1.37 (1.02–6.50)	0.702	1.66 (0.23–6.76)	1.17 (0.18–3.85)	0.173	0.59 (0.42–0.75)	1.60 (0.39–3.35)	0.267
P value	0.093	0.094		0.548	0.114		> 0.999	0.0499

SCC: Squamous cell carcinoma, NSCLC: Non-small cell-lung carcinoma, (Min-Max): Median (Minimum-Maximum),