Table 3.
Summary of additional phenotypic validation experiments for KpSC pan v2
|
Substrate* |
Predicted growth† |
TP |
TN |
FP |
FN |
Accuracy (%) |
|---|---|---|---|---|---|---|
|
2-Aminoethylphosphonate |
31/37 |
6 |
6 |
25 |
0 |
32.4 |
|
Beta-alanine |
37/37 |
17 |
0 |
20 |
0 |
46.0 |
|
Allantoin |
3/37 |
2 |
31 |
1 |
3 |
89.2 |
|
l-Ectoine |
5/41 |
1 |
34 |
4 |
2 |
85.4 |
|
Phenylpropanoate |
10/42 |
7 |
31 |
2 |
2 |
90.5 |
|
Uracil |
37/37 |
28 |
0 |
9 |
0 |
75.7 |
*Substrates were not present on Biolog PM1/PM2 plates, and were tested via an independent culture approach in aerobic conditions only (see Methods).
†Isolates tested include 37 KpSC for which Biolog microarray data were available. Two phenotypes were predicted as rare among this set of 37 KpSC, and hence additional isolates for which growth was predicted were selected from our collection; n=4 available for l-ectoine and n=5 for phenylpropanoate (see Table S5).