Fig. 5.

Unusually high rates of recombination at co-trimoxazole (SXT) resistance loci. The number of recombination events relative to point mutations (ρ/θ) (a), and the number of nucleotides changed by recombination events relative to point mutations (r/m) (b), among isolates with and without co-trimoxazole resistance determinants. Bars indicate 95 % confidence intervals. The number of recombination events per base pair (among base pairs with ≥1 event) in the core genome alignment. Line indicates the 99.5th percentile. The three loci with the most recombination events per base pair are indicated.