Table 3.
Association Between DANA Task Score and Neuropsychological Test Domain‐Specific Scores in the Framingham Heart Study (N=344)
| Task | Executive function | Attention and processing speed | Memory | |||
|---|---|---|---|---|---|---|
| Unadjusted | Adjusted* | Unadjusted | Adjusted* | Unadjusted | Adjusted* | |
| B±SE (P value) | B±SE (P value) | B±SE (P value) | B±SE (P value) | B±SE (P value) | B±SE (P value) | |
| DANA task, Code Substitution | ||||||
| ART for all trials | −0.001±0.0001 (<0.001†) | −0.001±0.0001 (<0.001†) | −0.0005±0.0001 (<0.001†) | −0.001±0.0001 (<0.001†) | −0.001±0.0001 (<0.001†) | −0.001±0.0001 (<0.001†) |
| ART for all correct test trials | −0.001±0.0001 (<0.001†) | −0.001±0.0001 (<0.001†) | −0.001±0.0001 (<0.001†) | −0.0007±0.0001 (<0.001†) | −0.001±0.0001 (<0.001†) | −0.001±0.0002 (<0.001†) |
| Cognitive efficiency | 0.04±0.01 (<0.001†) | 0.05±0.01 (<0.001†) | 0.03±0.01 (<0.001†) | 0.03±0.01 (<0.001†) | 0.04±0.01 (<0.001†) | 0.04±0.01 (<0.001†) |
| ART for all test trials | −0.001±0.0001 (<0.001†) | −0.001±0.0001 (<0.001†) | −0.001±0.0001 (<0.001†) | −0.001±0.0001 (<0.001†) | −0.001±0.0001 (<0.001†) | −0.001±0.0001 (<0.001†) |
| DANA task, Go/No‐Go | ||||||
| ART for all trials | −0.001±0.0003 (0.01†) | −0.001±0.0003 (0.02†) | −0.0004±0.0003 (0.25) | −0.0003±0.0003 (0.39) | −0.001±0.0004 (0.003†) | −0.001±0.0004 (0.007†) |
| ART for all correct test trials | −0.00002±0.0003 (0.9) | −0.000003±0.0003 (0.8) | −0.00002±0.0003 (0.94) | −00002±0.0003 (0.95) | −0.0001±0.0003 (0.88) | −0.0001±0.0004 (0.86) |
| Cognitive efficiency | 0.01±0.002 (<0.001†) | 0.01±0.002 (<0.001†) | 0.004±0.002 (0.04) | 0.004±0.002 (0.06) | 0.01±0.002 (0.004†) | 0.01±0.002 (0.01†) |
| ART for all test trials | −0.0001±0.0003 (0.80) | −0.0001±0.0003 (0.67) | −8.23e‐06±0.0003 (0.97) | −0.00003±0.0003 (0.91) | 1.09e‐06±0.0003 (0.99) | −0.00003±0.0003 (0.93) |
| DANA Task, Simple Reaction Time | ||||||
| ART for all trials | −0.002±0.001 (<0.001†) | −0.002±0.001 (0.001†) | −0.001±0.001 (0.02†) | −0.001±0.001 (0.03†) | −0.002±0.001 (0.003†) | −0.002±0.001 (0.007†) |
| ART for all correct test trials | −0.002±0.001 (0.001†) | −0.002±0.001 (0.003†) | −0.001±0.001 (0.02†) | −0.001±0.001 (0.04†) | −0.001±0.001 (0.08) | −0.001±0.001 (0.22) |
| Cognitive efficiency | 0.006±0.002 (<0.001†) | 0.006±0.002 (<0.001†) | 0.004±0.001 (0.01†) | 0.004±0.001 (0.02†) | −0.004±0.002 (0.02†) | −0.004±0.002 (0.04†) |
| ART for all test trials | −0.002±0.001 (0.001†) | −0.002±0.001 (0.005†) | −0.001±0.001 (0.04†) | −0.001±0.001 (0.09) | −0.002±0.001 (0.04†) | −0.001±0.001 (0.12) |
Executive function: Digit Span Backward and Trail Making Test‐Part B. Attention and processing speed: Digit Span Forward and Trail Making Test‐Part A. Memory: Logical Memory‐Immediate Recall and Delayed Recall. ART indicates average response time; B, unstandardized coefficients; and DANA, Defense Automated Neurocognitive Assessment.
*
Adjusted: covariates included age and education level.
†
Statistically significant.