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. 2024 Jan 12;13(2):e022557. doi: 10.1161/JAHA.121.022557

Table 5.

Baseline Fractional Shortening Z Scores and Changes in Z Score in Children With Dilated Cardiomyopathy by Percentile and by Outcome

FS Percentile FS‐z Death/Transplant Survived Sensitivity % Specificity %
Baseline <FS‐Z (true +) Baseline ≥FS‐Z (false −) Baseline ≥FS‐Z (true −) Baseline <FS‐Z (false +)
Outcome at 1 y
(n=137) (n=518)
25th −10.94 44 93 402 116 32.1 77.6
50th −9.04 83 54 277 241 60.6 53.5
75th −5.94 119 18 153 365 86.9 29.5
Outcome at 7 y
(n=241) (n=112)
25th −10.94 67 174 82 30 27.8 73.2
50th −9.04 132 109 53 59 54.8 47.3
75th −5.94 200 41 29 83 83.0 25.9
Change in FS percentile Change in FS Z score Change<FS‐Z (true +) Change ≥ FS‐Z (false −) Change ≥ FS‐Z (true −) Change<FS‐Z (false +) Sensitivity % Specificity %
Outcome at 1 y
(n=117) (n=479)
25th −0.18 50 67 380 99 42.7 79.3
50th 1.95 95 22 267 212 81.2 55.7
75th 5.50 111 6 134 345 94.9 28.0
Outcome at 7 y
(n=210) (n=105)
25th −0.18 85 125 85 20 40.5 81.0
50th 1.95 160 50 64 41 76.2 61.0
75th 5.50 197 13 33 72 93.8 31.4

Sensitivity and specificity of baseline echocardiographic LV fractional shortening Z score and change in baseline LV fractional shortening Zscore at follow‐up assessment for the prediction of death or cardiac transplant vs survival at 1 year and at 7 years in children with dilated cardiomyopathy for whom echocardiographic values were available. Values at the 25th, 50th, and 75th percentile of the range are shown. FS indicates fractional shortening; and LV, left ventricular.