Table 5.
Baseline Fractional Shortening Z Scores and Changes in Z Score in Children With Dilated Cardiomyopathy by Percentile and by Outcome
FS Percentile | FS‐z | Death/Transplant | Survived | Sensitivity % | Specificity % | ||
---|---|---|---|---|---|---|---|
Baseline <FS‐Z (true +) | Baseline ≥FS‐Z (false −) | Baseline ≥FS‐Z (true −) | Baseline <FS‐Z (false +) | ||||
Outcome at 1 y | |||||||
(n=137) | (n=518) | ||||||
25th | −10.94 | 44 | 93 | 402 | 116 | 32.1 | 77.6 |
50th | −9.04 | 83 | 54 | 277 | 241 | 60.6 | 53.5 |
75th | −5.94 | 119 | 18 | 153 | 365 | 86.9 | 29.5 |
Outcome at 7 y | |||||||
(n=241) | (n=112) | ||||||
25th | −10.94 | 67 | 174 | 82 | 30 | 27.8 | 73.2 |
50th | −9.04 | 132 | 109 | 53 | 59 | 54.8 | 47.3 |
75th | −5.94 | 200 | 41 | 29 | 83 | 83.0 | 25.9 |
Change in FS percentile | Change in FS Z score | Change<FS‐Z (true +) | Change ≥ FS‐Z (false −) | Change ≥ FS‐Z (true −) | Change<FS‐Z (false +) | Sensitivity % | Specificity % |
---|---|---|---|---|---|---|---|
Outcome at 1 y | |||||||
(n=117) | (n=479) | ||||||
25th | −0.18 | 50 | 67 | 380 | 99 | 42.7 | 79.3 |
50th | 1.95 | 95 | 22 | 267 | 212 | 81.2 | 55.7 |
75th | 5.50 | 111 | 6 | 134 | 345 | 94.9 | 28.0 |
Outcome at 7 y | |||||||
(n=210) | (n=105) | ||||||
25th | −0.18 | 85 | 125 | 85 | 20 | 40.5 | 81.0 |
50th | 1.95 | 160 | 50 | 64 | 41 | 76.2 | 61.0 |
75th | 5.50 | 197 | 13 | 33 | 72 | 93.8 | 31.4 |
Sensitivity and specificity of baseline echocardiographic LV fractional shortening Z score and change in baseline LV fractional shortening Zscore at follow‐up assessment for the prediction of death or cardiac transplant vs survival at 1 year and at 7 years in children with dilated cardiomyopathy for whom echocardiographic values were available. Values at the 25th, 50th, and 75th percentile of the range are shown. FS indicates fractional shortening; and LV, left ventricular.