Table 5.
compounds | cell line | CC50 (μM) | SCI |
---|---|---|---|
7c | CEM | 2.8 ± 0.31 | 14.4 |
Ramos | 7.0 ± 1.17 | 5.8 | |
HeLa | 10.3 ± 0.56 | 3.9 | |
SH-SY5Y | 49.5 ± 1.09 | 0.8 | |
HS-27 | 40.2 ± 4.75 | - | |
7e | Ramos | 6.2 ± 0.28 | >10 |
7f | CEM | 10.6 ± 0.22 | >10 |
Ramos | 9.1 ± 0.08 | >10 | |
7g | CEM | 10.7 ± 0.41 | >10 |
Ramos | 9.3 ± 0.01 | >10 | |
HeLa | 10.4 ± 0.58 | >10 | |
MDA-MB-231 | 9.8 ± 0.22 | >10 | |
7i | CEM | 9.6 ± 0.15 | 4.2 |
Ramos | 9.6 ± 0.14 | 4.2 | |
HeLa | 10.4 ± 0.16 | 3.8 | |
MDA-MB-231 | 9.8 ± 0.1 | 4.1 | |
SH-SY5Y | 21.8 ± 0.41 | 1.8 | |
HS-27 | 39.9 ± 1.95 | - | |
7j | Ramos | 10.0 ± 0.39 | >10 |
HeLa | 10.2 ± 0.52 | >10 | |
MDA-MB-231 | 10.3 ± 0.12 | >10 | |
SH-SY5Y | 52.3 ± 3.09 | >10 | |
7l | HeLa | 9.9 ± 0.25 | >10 |
SH-SY5Y | 91.1 ± 4.26 | >10 | |
7o | HeLa | 10.1 ± 0.04 | >10 |
7q | MDA-MB-231 | 55.8 ± 1.56 | >10 |
7r | CEM | 40.9 ± 3.16 | 1.4 |
SH-SY5Y | 16.0 ± 0.69 | 3.6 | |
HS-27 | 57.0 ± 8.45 | - | |
Pioglitazone | CEM | 0% @ 50 μM | - |
HeLa | 0% @ 10 μM | - | |
SAHA | CEM | 2.5 ± 0.13 | - |
HeLa | 2.8 ± 1.47 | - |
CC50 reported as average concentration ± std. deviation (μM); SCI = CC50HS‑27/CC50cancer; Nd*-Not determined